Seasonal variations in daily mortality associated with exposure to particulates, in Campo Grande, Brazil/ Variaciones estacionales de la mortalidad diaria asociada a la exposición a partículas, en Campo Grande, Brasil/ Variações sazonais na mortalidade diária associada à exposição a partículas, em Campo Grande, Brasil

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Respiratory Diseases, Hospitalization, Air Pollutants


Obcjetive: to investigate short-term effects of air pollution, climate variability on respiratory morbidity and mortality from 2005 to 2020. Method: the study was carried out in the city of Campo Grande, Mato Grosso do Sul, Brazil. Daily counts of hospital admissions from 2005 to 2020 were analyzed in relation to daily variations in atmospheric pollutants (NO2, O3) from the Aurea satellite column, OMI sensor. Poisson regression in generalized additive models was used for analysis. The models were adjusted for the effects of temporal trend, seasonality, meteorological factors and autocorrelation. Results: there was, in the period, an increasing trend in mortality rates and hospital admissions, with an increase in the proportion of deaths from respiratory diseases in relation to other causes. Conclusion: respiratory diseases are worrying causes of hospitalization and death in the population. The results found are consistent with studies that point to an association between short-term variations in air pollutants and the increase in morbidity and mortality in large urban centers.


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Hastie TJ, Tibshirani RJ. Monographs on statistics and applied probability 43: generalizes additive models. Pediatr Pulmonol. 1990; 31(2):106-113.

Wood, SN. Generalized additive models: an introduction with R. Boca Raton: Chapman & Hall/CRC; 2006.

Daumas RP, Mendonça GAS, De León PA. Poluição do ar e mortalidade em idosos no município do Rio de Janeiro: análise de série temporal. Cad Saúde Pública. 2004; 20:311-9.

Souza A, Aristone F, Sabbah I, Santos Das. Temperature, hospital admissions in Campo Grande, MS, Brazil: a time-series analysis. Glob Adv Res J of Med and Med Sci. (Garjmms). 2015; 4:110-116.

Nascimento AP, Santos JM, Mill JG, Souza JB, Reis Júnior NC, Reisen VA. Associação entre concentração de partículas finas na atmosfera e doenças respiratórias agudas em crianças. Rev Saúde Pública. 2017; 51:3.

Junger W, Leon AP. Ares: environment air pollution epidemiology. A library for time series analysis. Vienna: The Comprehensive R Archive Network. 2011.

Mccullagh P, Nelder JA. Generalized linear models. London: ChapmanandHall.1989.

Tadano YS, Ugaya CML, Franco AT. Método de regressão de Poisson: metodologia para avaliação do impacto da poluição atmosférica na saúde populacional. Amb Soc. 2009; 12(2):241-255.

Johnson RA, Wichern DW. Applied multivariate statistical analysis. Prentice Hall: Upper Saddle River; 2002.

Latorre MRDO. Câncer em Goiânia: análise da incidência e da mortalidade no período de 1988 a 1997 [Tese de livre-docência]. São Paulo: Faculdade de Saúde Pública da USP; 2001.

Jacobson LSV, Oliveira BFA, Schneider R, Gasparrini A, Hacon SS. Mortality risk from respiratory diseases due to non-optimal temperature among brazilian elderlies. Int J Environ Res Public Health. 2021; 18:5550.

Matos EP, Reisen VA, Serpa FS, Pprezotti Filho PR, Leite MFS. Análise espaço-temporal do efeito da poluição do ar na saúde de crianças. Cad Saúde Pública. 2019; 35(10).

Olstrup H, Johansson C, Forsberg B, Åström C. Association between Mortality and Short-Term Exposure to Particles, Ozone and Nitrogen Dioxide in Stockholm, Sweden. Int J Environ Res Public Health. 2019; 21:16(6):1028.

De Souza A, Santos DA. Temperatura como um fator de risco para internações hospitalares em 70 cidades do MS. Cêinc Natura. 2016; 38:1512.

Riva DR, Magalhães CB, Lopes AA, Lanças T, Mauad T, Malm O, et al. Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice. Inhal Toxicol. 2011; 23(5):257-267.

Lin CA, Martins MA, Farhat SC, Pope CA 3rd, Conceição GM, Anastácio VM, et al. Air pollution and respiratory illness of children in São Paulo, Brazil. Paediatr Perinat Epidemiol. 1999; 13(4):475-488.

Martins MC, Fatigati FL, Véspoli TC, Martins LC, Pereira LA, Martins MA, et al. Influence of socioeconomic conditions on air pollution adverse health effects in elderly people: an analysis of six regions in São Paulo, Brazil. J Epidemiol Community Health. 2004; 58(1):41-46.

Pope CA 3rd, Burnett RT, Thun MJ, Calle EE, Krewski D, Ito K, et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA. 2002; 287(9):1132-1141.

Baxter LA, Finch SJ, Lipfert FW, Yu Q. Comparing estimates of the effects of air pollution on human mortality obtained using different regression methodologies. Risk Anal. 1997; 17:273-8.

Mazzoli-Rocha F, Carvalho GM, Lanzetti M, Valença SS, Silva LF, Saldiva PH, et al. Respiratory toxicity of repeated exposure to particles produced by traffic and sugar cane burning. Respir Physiol Neurobiol. 2014; 191:106-113.

Souza JB, Reisen VA, Franco GC, Ispány M, Bondon P, Santos JM. Generalized additive models with principal component analysis: an application to time series of respiratory disease and air pollution data. J R Stat Soc. 2018; 67:453-80.

Mauad T, Rivero DH, De Oliveira RC, Lichtenfels AJ, Guimarães ET, De Andre PA, et al. Chronic exposure to ambient levels of urban particles affects mouse lung development. Am J Respir Crit Care Med. 2008; 178(7):721-728.

Barros MLT, Groth EE, Veras M, Furuya TK, De Souza XCN, Ribeiro Júnior G, et al. Pre and postnatal exposure of mice to concentrated urban PM2.5 decreases the number of alveoli and leads to altered lung function at an early stage of life. Environ Pollut. 2018; 241:511-520.

Rodrigues PCO, Ignotti E, Rosa AM, Hacon SS. Spatial distribution of asthma-related hospitalizations of the elderly in the Brazilian Amazon. Rev Bras Epidemiol. 2010;13(3):523-532.

Jedrychowski WA, Perera FP, Maugeri U, Mroz E, Klimaszewska-Rembiasz M, Flak E, et al. Effect of prenatal exposure to fine particulate matter on ventilatory lung function of preschool children of non-smoking mothers. Pediatr. Perinat. Epidemiol. 2010; 24(5):492-501.

Hamra GB, Guha N, Cohen A, Laden F, Raaschou-Nielsen O, Samet JM, et al. Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis. Environ Health Perspect. 2014; 122(9):906-911.

Longo KM, Freitas SR, Andreae MO, Yokelson R, Artaxo P. Biomass burning in Amazonia: emissions, long-range transport of smoke and its regional and remote impacts. Washington DC: AGU; 2009.

Chen Z, Salam MT, Eckel SP, Breton CV, Gilliland FD. Chronic effects of air pollution on respiratory health in Southern California children: findings from the Southern California Children's Health Study. J Thorac Dis. 2015; 7(1):46-58.

Li J, Sun S, Tang R, Qiu H, Huang Q, Mason TG, et al. Major air pollutants and risk of COPD exacerbations: a systematic review and meta-analysis. Int J Chron Obstruct Pulmon Dis.2016; 11:3079-3091.

De Souza A, Andrade FA, Oguntunde PE, Arsic M, Silva DAS. Climate indicators and the impact on morbidity and mortality of acute respiratory infections. Adv Stud in Med Sciences. 2018; 6:5-20.

Wilks SD. Statistical methods in the atmospheric sciences. San Diego: Academic Press; 2006.

Giles LV, Koehle MS. The health effects of exercising in air pollution. Sports Med. 2014; 44(2):223-249.

Di Q, Dai L, Wang Y, Zanobetti A, Choirat C, Schwartz JD, et al. Association of short-term exposure to air pollution with mortality in older adults. JAMA. 2017; 318(24):2446-2456.




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Soares Casaes Nunes, R., Francisco de Oliveira-Júnior J. ., Carvalho Abreu, M. ., Aristone, F. ., Alves Fernandes, W. ., de Souza, A., … Martins de Souza, D. (2022). Seasonal variations in daily mortality associated with exposure to particulates, in Campo Grande, Brazil/ Variaciones estacionales de la mortalidad diaria asociada a la exposición a partículas, en Campo Grande, Brasil/ Variações sazonais na mortalidade diária associada à exposição a partículas, em Campo Grande, Brasil. Journal Health NPEPS, 7(1). Recuperado de



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